New therapeutic possibilities for various diseases are made possible via mRNA. The adaptability of in vitro transcribed (IVT) mRNA is largely due to its simpler cell-free manufacture, cell cycle ...

As the first step in many workflows, in vitro transcription (IVT) has quickly emerged as an essential part of successful mRNA therapeutic manufacturing processes, optimizing and accelerating ...

In vitro-transcribed (IVT) mRNA encoding therapeutic proteins, or viral antigens, had great potential for treating or preventing various diseases, but for years the body’s inflammatory response ...

Enter Primrose Bio with its offering of commercially available, proprietary, best-in-class RNA polymerases for mRNA synthesis by in vitro transcription (IVT) (Fig. 1). Primrose Bio’s Prima ...

The findings, in mouse models and isolated human brain tissue, were published in Nature Materials in a paper titled "Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to the ...

and IVT innovators and decision-makers. Join more than 100 experts in Upstream & Downstream Process Development, Analytical Development, CMC, Manufacturing, and Drug Product at the 3rd mRNA ...

Aldevron, a global leader in the production of DNA, RNA and protein, has launched its latest innovation, Alchemy™ cell-free DNA technology. This revolutionary technology represents a significant ...

PCR is effective at making blunt-ended DNA, which is useful for both IVT templates and CRISPR donor DNA. The CRISPR market, particularly in cell and gene therapy, is less mature than mRNA but ...