Cleft lip and cleft palate are among the most common birth defects, occurring in about one in 1,050 births in the United ...

Peter Rickgauer et al, Structural dynamics of human ribosomes in situ reconstructed by exhaustive high-resolution template matching, Molecular Cell (2024). DOI: 10.1016/j.molcel.2024.11.003 ...

That process led to the group discovering a lasso peptide that exhibited broad-spectrum antibiotic activity and was effective at killing both gram-positive and gram-negative pathogenic bacteria, along ...

HHMI scientists and their colleagues discover a new mechanism of protein synthesis. Ribosomes are the cell’s molecular machines, responsible for translating genetic information in messenger RNA into ...

During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

When your social media account starts spewing out nonsensical or threatening status updates, it's safe to assume that it has been hacked and must be shut down.

In the males, core ribosomes were unable to pick up the slack—and as a ... Ware similarly expresses excitement about what this study means for human health. “One would expect that these results would ...

Only recently has the ribosome—one of the oldest molecular machines in evolutionary terms—been recognized as an active regulator of gene expression at the level of protein biosynthesis.

Cutting-edge research includes the study of the human ribosome to combat cancer, interfacing machines with the human brain to better understand neurological characteristics, and decoding the ...

Within the ribosome, the mRNA and aminoacyl-tRNA complexes ... In bacterial mRNA, the 5' UTR is normally short; in human mRNA, the median length of the 5' UTR is about 170 nucleotides.

Protein waste turned into antibiotics as a defence strategy of human cells Jangra and colleagues then considered whether the antibiotic target might be the ribosome, given that no mutations in a ...

Wright says this lack of toxicity to human cells is because human ribosomes are just different enough from bacterial ribosomes that lariocidin can’t bind to them. The team then infected mice with A.