With the help of their new development, they have also analyzed how novel influenza viruses use alternative receptors to enter target cells. The results were published in two papers in the journal ...

Discovering that ACE2 is the host cell receptor for NeoCoV and PDF-2180, which are closely related to the deadly human pathogen MERS-CoV, was totally unexpected and opens new avenues to prepare ...

Discovering that ACE2 is the host cell receptor for NeoCoV and PDF-2180, ... Citation: Bat virus receptor studies vital to predict spillover risk (2022, December 7) ...

In bats, two close virus relatives of the coronavirus MERS-CoV, the cause of Middle-East Respiratory Syndrome, use the ACE2 receptor as an entry point into bat cells. These receptors have some ...

While most merbecoviruses appear unlikely to be able to infect humans, HKU5 viruses— which have been found across Asia, Europe, Africa, and the Middle East—were shown to use the host receptor ...

The study authors focused on altering one of H5N1’s surface proteins, hemagglutinin, which contains the binding site that allows the virus to latch onto host cell receptors and kick-start infection.

Viruses take advantage of proteins or receptors on the surfaces of human cells to gain entry into those cells, and start an infection. Human cells have receptors that can interact with viral proteins, ...

"These viruses are so closely related to MERS, so we have to be concerned if they ever infect humans," said virologist Michael Letko.

Antiretroviral therapy (ART) helps people living with HIV suppress the virus to undetectable levels, but those patients must take these medications for the rest of their lives, and for some, the drugs ...

The avian and human influenza A virus receptors sialic acid (SA)-α2,3 and SA-α2,6 are widely expressed in the bovine mammary gland. bioRxiv.org. Posted May 3, 2024. doi: 10.1101/2024.05.03 ...

The bat influenza A virus subtype H18N11 induces nanoscale MHCII clustering upon host cell attachment. Nature Communications , 2025; 16 (1) DOI: 10.1038/s41467-025-58834-y Cite This Page : ...

A novel microscopy method enables detailed analysis of influenza virus interactions with host cells, revealing that some strains, such as H18N11, use MHC class II protein receptors instead of ...