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Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power.
A Ludwig Cancer Research study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive ...
Histone modification is an epigenetic mechanism that enables fine-tuning of gene expression. Mutation or dysregulation of proteins associated with histone | Ebooks ...
A Ludwig Cancer Research study has identified a novel strategy for treating acute myelogenous leukemia (AML), an aggressive blood cancer for which the median survival time following diagnosis remains ...
The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...
In animal cells, DNA can be modified by methylation of cytosine residues in CpG dinucleotides, and the N-terminal tails of histone proteins are subject to a wide range of different modifications ...
Neutrophils in urine extrude their DNA to create large webs that catch and kill pathogens.
Now, Warnecke and colleagues are challenging the idea that these space-saving proteins are not commonplace in bacteria. In a preprint uploaded to bioRxiv this January that has yet to undergo peer ...
Historically, therapies for ASD and ID have primarily targeted managing symptoms, such as behavioral issues or communication ...
Beyond its canonical role in H3K27 trimethylation, EZH2 has been found to regulate non-histone proteins, activating pathways that promote metastasis and chemotherapy resistance. By targeting EZH2 ...