Epigenetic reprogramming holds promise for reversing aging, addressing cellular aging mechanisms and paving the way for ...

The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact ...

Neutrophils in urine extrude their DNA to create large webs that catch and kill pathogens.

Scientists at the University of California, Riverside, have discovered how adult stem cells retain their regenerative power.

This useful study reports a method to detect and analyze a novel post-translational modification, lysine acetoacetylation (Kacac), finding it regulates protein metabolism pathways. The study unveils ...

Citrullination, a transformative protein post-translational modification, is gaining recognition for its wide-ranging impact on cellular function and human disease.

Now, Warnecke and colleagues are challenging the idea that these space-saving proteins are not commonplace in bacteria. In a preprint uploaded to bioRxiv this January that has yet to undergo peer ...

This enzyme is able to silence specific DNA sections by epigenetically modifying histone proteins that package the DNA. These modifications ensure that the DNA is densely packed as heterochromatin ...

modification and mutation locations are indicated by boxes and lines. For clarity, connections are only shown to a single copy of each histone protein.