Semin Liver Dis. 2005;25(4):381-391. Although a very similar clinicopathological syndrome occurs with iron overload secondary to iron-loading anemia such as thalassemia major or sideroblastic ...

The iron overload involves various organs ... It is responsible for severe hypochromic microcytic anemia (the normal fate of transferrin iron being to provide bone marrow for red blood cell ...

This condition leads to anemia, hemolysis (the destruction of red blood cells), and often results in iron overload due to the body's inability to properly manage iron levels. There are several ...