Figure 4: H2B ubiquitination of the p21 gene correlates with p53-dependent transcriptional activation. Although H2B ubiquitination in mammalian cells had already been reported more than 25 years ...

Figure 6: A model of H2B Tyr37 phosphorylation upstream of the major histone gene cluster Hist1 suppresses histone mRNA transcription. Overall, whether in mammals or in yeast, H2B Tyr37 ...

Errors in this process can alter the epigenetic landscape, gene expression and cell identity ... are preserved as a hexamer, with one H2A-H2B dimer missing. Another protein that involved in ...

H2B.8-mediated condensation is sufficient for immotile sperm and compatible with gene activity.” The team also speculate that such nuclear condensation mechanisms are likely to operate outside ...

Chromatin remodeling is an important mechanism of regulating eukaryotic gene expression ... 2 copies each of 4 histone proteins namely H2A, H2B, H3, and H4 (histone octamer).