The platform technology will take the form of a small-molecule drug conjugate made of urokinase, folic acid and a linker, which will then activate prodrugs in the proximity of tumours. Strong ...

AstraZeneca has been busy in recent years pumping up its oncology pipeline via a shopping list of assets and companies. | ...

For example, when we inactivate (knock out) the folate receptor (Forl1) gene-its protein product which is a receptor molecule that brings vitamin B9 (folic acid) into cells is eliminated, and the ...

The B vitamin folate reduces levels of homocysteine, a molecule that is a risk factor for cardiovascular disease and stroke. Blumberg recommends that elderly people take 400 micrograms per day to ...