Since 2016, the FDA has received 25 reports of unapproved epinephrine nasal solution being confused with approved epinephrine injection.

drugs (particularly adrenaline (epinephrine)) may be delivered by the endotracheal route in double or triple doses. The pharmacological treatment of VF/pulseless VT is of secondary importance to early ...

Similarities between the packaging for certain intranasal and intravenous epinephrine products may result in inappropriate administration, according to the Food and Drug Administration (FDA).