Ribosomes turn upside-down in hungry cells ... Medicine explored it in greater detail using single-particle cryo-electron microscopy and cryo-electron tomography. The results are published in ...

It provides a serious piece of heft to the hypothesis that specialized ribosomes not only exist but have important functional consequences in cellular processes. —Vassie Ware, Lehigh University ...

In 1974, Palade himself took the stage to deliver his own Nobel lecture. The foundation for much of his work was electron microscopy (EM), which Palade used to visualize the components of the cell.

Within a cell, DNA carries the genetic code for building proteins. To build proteins, the cell makes a copy of DNA, called mRNA. Then, another molecule called a ribosome reads the mRNA, translating it ...

Ribosomes are the cell’s molecular machines ... Peter Shen, a postdoctoral researcher in Frost’s lab, isolated RQCs from yeast cells and used cryo-electron microscopy to develop three-dimensional ...

LMU structural biologist Roland Beckmann, in collaboration with researchers at the Max Planck Institute for Biochemistry and the Institut Pasteur (Paris), has now shown that there is a direct ...

He recognized that ribosomes exist free in the cytoplasm ... Palade's genius, however, was his masterful combination of electron microscopy with cell fractionation and biochemical analysis ...

Scanning Transmission Electron Microscopy (STEM) and Transmission Electron Microscopy (TEM) are two closely related imaging techniques used in material science, nanotechnology, and biology for ...

The 3D electron microscopy imaging is available using Serial Block Face (SB-EM) and Focused Ion Beam Scanning Electron Microscopy (FIB-SEM) or Electron Tomography (ET) Electron tomography is TEM based ...