The Hsu lab found that when IS110 excises itself from a genome, the non-coding DNA ends are joined together to produce an RNA molecule – the bridge RNA – that folds into two loops.

Your DNA is continually damaged by sources both inside and outside your body. One especially severe form of damage called a ...

In the Protein Engineering and Evolution Unit's latest publication in Nucleic Acids Research, the team presents an engineered RNA methyltransferase, which can be used to study the role of RNA ...

AlphaGenome scores mutation effects across coding and non-coding DNA, bringing gene insights to the base-pair level.

For a long time DNA has enjoyed the spotlight as the bearer of all genetic information, but increasingly RNA is emerging as the power behind the scenes—the molecule that controls gene expression.

In their quest to identify the best tool for the task, the researchers tested a variety of methods against a real biological dataset with known matching DNA-RNA pairs.

Twist RNA sequencing tools enable minimal hands-on time and increase the scale of samples sequenced through utilizing automation. They are compatible with a wide range of sample inputs, including ...

Nucleic acid quantification (NAQ) is the process of determining the concentration of DNA or RNA in a sample. Accurate NAQ is crucial in various molecular biology applications, including PCR, ...

Artificial intelligence can predict on- and off-target activity of CRISPR tools that target RNA instead of DNA, according to new research published in Nature Biotechnology. CRISPR is a gene editing ...

Traditionally, treatments and gene-editing tools have focused almost exclusively on DNA or proteins. Our findings suggest that modifying RNA in different ways could also influence how cells ...