Researchers have previously tried sticking down one end of a DNA molecule to stretch it out, but found that the thermal fluctuations could still cause movement and blurring. "Stretching DNA refers ...

And strikingly, the team found that it did: the human SMC protein cohesin does indeed not only pull DNA into a loop ... processes is vital for tracking down the molecular origins of these serious ...

Kingston wanted to reverse the process and use a DNA probe to pull down all proteins associated with a targeted DNA locus in vivo. He is quick to point out that this idea is not new ...

They next broke up the DNA from each cell type and isolated histones that bore specific modifications, using antibodies and beads to pull down the modified histone of interest and its associated ...