As for cost differences, 2 years of tacrolimus and cyclosporine treatment are estimated to be $1,319 and $1,561, respectively, while 8 weeks of cyclophosphamide is $19 for a 44-lb child in the U.S ...

Using genetic markers to adjust initial doses of cyclosporine or tacrolimus may prove difficult, considering the variety of polymorphisms known to affect CYP3A4, CYP3A5, and MDR1. The current ...

An objective measure of compliance with immunosuppressive drugs was also adopted by documenting the patient's trough blood concentrations of cyclosporine or tacrolimus. Noncompliance was defined ...