A new study published in Biochemistry sheds light on how bacteria regulate their genes, challenging long-held assumptions ...

Cyclic AMP Signaling and Protein Kinase Regulation; ... Epac1-dependent pathways, leading to altered Ca2+-handling in cardiomyocytes and shedding light on arrhythmogenic mechanisms [4].

Cyclic adenosine monophosphate (cAMP) is one of the most important signaling molecules in virtually all cell types and organisms. We describe cAMPr, a new single-wavelength cAMP sensor.

The innate immune response is the body's first line of defense against infection, and a successful immune defense takes a ...

The cyclic GMP–AMP synthase (cGAS) enzyme binds to viral DNA, tumor DNA, or our own aberrant DNA. DNA binding activates cGAS to synthesize cyclic GMP–AMP (cGAMP) from ATP and GTP nucleotides.

Researchers have identified a novel cyclic signaling in the dermis that coordinates stem cell activity and regulates regeneration in large populations of hairs in animal models. The 'dermal clock ...

Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that underpins a wide array of physiological processes. It activates multiple effector pathways, most notably protein kinase ...