An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...
Intestinal cells, for example ... Invasin sustains long-term expansion of primary epithelial cells as 2D organoid sheets, Proceedings of the National Academy of Sciences (2024).
This marks a significant milestone as SIGX1094 is the first pipeline drug discovered using AI and organoid disease model to enter clinical trials, and the first targeted therapy candidate to ...
We offer diverse products and services, including cardiac disease modeling, organoid identification ... understanding and advance disease modeling and therapeutic strategies. Intestinal-related ...
Colorectal cancer (CRC) is a major health problem, with an alarming increase of early-onset CRC (EO-CRC) cases among individuals under 50 years of age. This trend shows the urgent need for ...
Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...