To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian ...

In this study, we compared the synonymous codon usage patterns between the nucleocapsid and spike genes of CoVs, and C-type lectin domain (CTLD) genes of human and mouse on the codon basis.

Different organisms show different patterns of codon usage, which can reflect mutation biases, selection for efficient and accurate translation, and even viral adaptation to host codon usage. Codons ...

Pachysolen tannophilus TOM JEFFERIES When recombinant protein expression fails, a scientist might blame faulty sequence data or a kit gone bad. But in the case of the ascomycete yeast Pachysolen ...

A study conducted by researchers in the US has revealed that optimization of codon for bacterial expression causes the production of an inactive enzyme non-structural protein 12 (Nsp12), a ...

They also noted that TF-imposed constraint appears to be a major driver of codon usage bias. “Conversely, the regulatory code has been selectively depleted of TFs that recognize stop codons ...