small molecules to directly inhibit the two key proteases in the coagulation cascade: thrombin and factor Xa (FXa). The recent approval of dabigatran etexilate for the prevention of venous ...

Factor XIa Inhibitor: A type of anticoagulant that specifically targets and inhibits factor XIa, a protein involved in the coagulation cascade. Atrial Fibrillation: An irregular and often rapid ...

The ability to inhibit both clot-bound and free thrombin ... its enzymatic activity and can continue to stimulate the coagulation cascade. [12] Dr. Gulseth has been a paid consultant to Aventis ...

Moreover, platelets, which play a central role in the coagulation cascade, release numerous factors that stimulate or inhibit angiogenesis. In addition elements of the coagulation cascade act as ...

and initiate the activation of the coagulation cascade when they come into contact with blood. Analyses by the study authors confirm that mucosal bleeding in the mouth of these patients is indeed ...