During interphase, individual chromosomes are not visible, and the chromatin appears diffuse ... Prometaphase is an extremely dynamic part of the cell cycle. Microtubules rapidly assemble and ...

It all has to do with its concentration gradient in the cell. Ran binds either ... was that disruption of the Ran GTPase cycle has a vast impact on chromatin decondensation and the reestablishment ...

Chromatin, the name for this packaging ... The cell can still divide with the slower cycle, but the new cells frequently find it difficult to develop and are unable to divide again.

These modifications alter chromatin structure ... Downregulated genes were often involved in the mitotic cell cycle and RNA ...

DREAM’s involvement in protecting somatic cell differentiation suggests that transcriptional suppression of both “germness” and the cell cycle governs the establishment ... complex forms and functions ...

Future work will define how the transgenerational inheritance of chromatin affects gene expression throughout an organism's life cycle. These projects will allow us to uncover general principles of ...

proliferation and cell cycle, growth factor receptors, cytokines/STATs, nuclear receptors/transcriptional, chromatin regulatory, and metabolism proteins. We continuously work together with BCM ...