Scientists at St. Jude Children’s Research Hospital used a series of cryo-EM structures to visualize dynamics pivotal to ...

During interphase, individual chromosomes are not visible, and the chromatin appears diffuse ... Prometaphase is an extremely dynamic part of the cell cycle. Microtubules rapidly assemble and ...

Chromatin remodeling plays a vital role in gene regulation, affecting how DNA is accessed. Disruptions in this process can ...

Chromatin, the name for this packaging ... The cell can still divide with the slower cycle, but the new cells frequently find it difficult to develop and are unable to divide again.

It all has to do with its concentration gradient in the cell. Ran binds either ... was that disruption of the Ran GTPase cycle has a vast impact on chromatin decondensation and the reestablishment ...

Northwestern Medicine scientists have uncovered new details about the genetic structure of ovarian cancer stem cells, according to a study published in Advanced Science. Inside cells, DNA mixes ...

DREAM’s involvement in protecting somatic cell differentiation suggests that transcriptional suppression of both “germness” and the cell cycle governs the establishment ... complex forms and functions ...

The work was published today in Cell Research. Chromatin comprises sections of DNA wrapped around proteins called histones to form nucleosomes collectively. One chromatin remodeling mechanism ...

Research published in Cell Research from Mario Halic, PhD, St. Jude Department of Structural Biology, revealed 13 distinct ...