A landmark review in Nature Reviews Genetics dissects the rare and common genetic variants that shape human height. The paper explains how monogenic and polygenic factors converge on key growth ...

In humans, the mutations associated with achondroplasia patients are mainly ... biomedical research of molecular biology, molecular genetics, and cell biology, including but not limited to cell ...

At the core of achondroplasia's pathology lies the hyperactivation of FGFR3, which impairs not only the growth of long bones but also affects cranial, spinal, and vertebral development. The ...

A recent publication in Genes & Diseases has delivered a compelling synthesis of the latest insights into the cellular ...