"My thanks to all of you as we start this new adventure together. Tonight, and always, we're here for you."Llamas also introduced a new series during his debut episode called "The Cost of Denial," which he explained is "a spotlight on the issues millions of American face across healthcare and homeownership when it comes to insurance coverage.

Holt is set to anchor his final broadcast and focus on a full-time role at "Dateline" after working the nighttime segment for a decade.