We dive into the San Francisco 49ers' 2025 NFL odds, review their offseason and preview their season from a betting perspective

With the NFL preseason buzz building, one voice offering rare insight into the San Francisco 49ers ’ mindset isn’t from inside the locker room. Kristin Juszczyk, wife of 49ers fullback Kyle Juszczyk, recently spoke in an exclusive interview about what truly sets the team apart: camaraderie, recovery and readiness.

Jake Brendel is locked in as a starter for the San Francisco 49ers for the fourth straight season, barring something significant and out of the ordinary happening. Brendel has been the definition of serviceable for the 49ers, which is why he checks in as the 20th most important 49ers player.

Think you can figure out which Niners player we’re talking about? You’ll get five clues to figure him out in our new guessing game!

San Francisco 49ers placed six players on the Active/Physically Unable to Perform list and two on the Active/Non-Football Injury list ahead of training camp.

San Francisco 49ers to have a bounce-back season. The 49ers are healthier, younger, and have Robert Saleh back. They have alr