Laclede is a city in Linn County, Missouri. The population was 305 at the 2020 census, down from 345 in 2010. Laclede was platted in 1853. T…Laclede is a city in Linn County, Missouri. The population was 305 at the 2020 census, down from 345 in 2010. Laclede was platted in 1853. The city was named for Pierre Laclède, the founder of St. Louis.